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甘露糖苷酶2抗体
半岛bd体育手机客户端 介绍
靶标:
MANEA 半岛bd体育手机客户端 别名: ENDO; hEndo; MANEA; mannosidase endo-alpha; mannosidase endo-alpha; glycoprotein endo-alpha-1,2-mannosidase; alpha 1,2-endomannosidase; endo-alpha mannosidase; endomannosidase; mandaselin; 甘露糖苷酶2; 背景信息:
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans.
宿主:Rbt |
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