半岛bd体育手机客户端 介绍
靶标：
ALG12 半岛bd体育手机客户端 别名： CDG1G； ECM39； PP14673； hALG12； ALG12； ALG12 alpha-1,6-mannosyltransferase； ALG12 alpha-1,6-mannosyltransferase； dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase； asparagine-linked glycosylation 12 homolog (S. cerevisiae, alpha-1,6-mannosyltransferase)； asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)； asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog； asparagine-linked glycosylation protein 12 homolog； dol-P-Man dependent alpha-1,6-mannosyltransferase； dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase； dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase； dolichyl-P-mannose:Man-7-GlcNAc-2-PP-dolichyl-alpha-6-mannosyltransferase； mannosyltransferase ALG12 homolog； membrane protein SB87； 背景信息：
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.
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