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钙蛋白酶5抗体
半岛bd体育手机客户端 介绍
靶标:
Htra3 半岛bd体育手机客户端 别名: 2210021K23Rik; 9530081K03Rik; Prsp; Tasp; Htra3; HtrA serine peptidase 3; HtrA serine peptidase 3; serine protease HTRA3; high-temperature requirement factor A3; pregnancy-related serine protease; probable serine protease HTRA3; toll-associated serine protease; 钙蛋白酶5; 背景信息:
Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440)-binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.
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