闈舵爣锛欬p style="text-indent: 2em;">Slx1b

浜у搧鍒悕锛欬p style="text-indent: 2em;">1110030E23Rik锛 2410170E21Rik锛 4833422P03Rik锛 AI853643锛 Giyd1锛 Giyd2锛 Slx1b锛 SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)锛 SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)锛 structure-specific endonuclease subunit SLX1锛 GIY-YIG domain containing 2锛 GIY-YIG domain-containing protein 1锛 DNA淇铔嬬櫧GIYD2锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.