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蛋白酶体PSMα8抗体
半岛bd体育手机客户端 介绍
靶标:
Psma8 半岛bd体育手机客户端 别名: 2410072D24Rik; Psma8; proteasome subunit alpha 8; proteasome subunit alpha 8; proteasome subunit alpha type-8; alpha4s; proteasome (prosome, macropain) subunit, alpha type, 8; proteasome alpha 4 subunit; proteasome alpha 8 subunit; 蛋白酶体PSMα8; 背景信息:
Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.
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