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MEX3A蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
Mex3a 半岛bd体育手机客户端 别名: 2700083E18Rik; Gm411; Rkhd4; Mex3a; mex3 RNA binding family member A; mex3 RNA binding family member A; RNA-binding protein MEX3A; mex3 homolog A; ring finger and KH domain containing 4; MEX3A蛋白; 背景信息:
Rkhd4, also known as MEX3A is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd4, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. While Rkhd2 has been suggested to be associated with susceptibility to essential hypertension type 8, the function of Rkhd4 remains unknown. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
宿主:Rbt |
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