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凋亡诱导蛋白D抗体
半岛bd体育手机客户端 介绍
靶标:
Plekhf1 半岛bd体育手机客户端 别名: 1810013P09Rik; APPD; LAPF; PHAFIN1; ZFYVE15; Plekhf1; pleckstrin homology domain containing, family F (with FYVE domain) member 1; pleckstrin homology domain containing, family F (with FYVE domain) member 1; pleckstrin homology domain-containing family F member 1; PH domain-containing family F member 1; lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; 凋亡诱导蛋白D; 背景信息:
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
宿主:Rbt |
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