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前细胞胀亡受体诱导膜损伤蛋白抗体
半岛bd体育手机客户端 介绍
靶标：
Tmem123 半岛bd体育手机客户端 别名： 2310075C12Rik； Tmem123； transmembrane protein 123； transmembrane protein 123； porimin； pro-oncosis receptor inducing membrane injury； 前细胞胀亡受体诱导膜损伤蛋白； 背景信息：
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008],
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