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10号染色体开放阅读框4抗体
半岛bd体育手机客户端 介绍
靶标:
Fra10ac1 半岛bd体育手机客户端 别名: 5730455O13Rik; AI448293; Fra10ac1; FRA10AC1 homolog (human); FRA10AC1 homolog (human); protein FRA10AC1 homolog; 10号染色体开放阅读框4; 背景信息:
C10orf4, also known as FRA10A or FRA10AC1, is a 315 amino acid nuclear protein that is expressed strongly in kidney, liver, heart, brain and skeletal muscle. Defects in the gene encoding C10orf4 are characterized by an expansion of a polymorphic CGG repeat within the 5'-UTR of the gene; an event that is thought to cause folate-sensitive fragile site FRA10A expression. Expression of this mutated FRA10A protein may be associated with tumorigenesis, neurological disorders and mental retardation. C10orf4 is believed to be conserved between species. Five isoforms of C10orf4, all of which differ in their C-termini, are expressed due to alternative splicing events.
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