闈舵爣锛欬p style="text-indent: 2em;">Fra10ac1

浜у搧鍒悕锛欬p style="text-indent: 2em;">5730455O13Rik锛 AI448293锛 Fra10ac1锛 FRA10AC1 homolog (human)锛 FRA10AC1 homolog (human)锛 protein FRA10AC1 homolog锛 10鍙锋煋鑹蹭綋寮€鏀鹃槄璇绘4锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">C10orf4, also known as FRA10A or FRA10AC1, is a 315 amino acid nuclear protein that is expressed strongly in kidney, liver, heart, brain and skeletal muscle. Defects in the gene encoding C10orf4 are characterized by an expansion of a polymorphic CGG repeat within the 5'-UTR of the gene; an event that is thought to cause folate-sensitive fragile site FRA10A expression. Expression of this mutated FRA10A protein may be associated with tumorigenesis, neurological disorders and mental retardation. C10orf4 is believed to be conserved between species. Five isoforms of C10orf4, all of which differ in their C-termini, are expressed due to alternative splicing events.