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软骨基质相关蛋白UCMA抗体
软骨基质相关蛋白UCMA抗体图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Anti-Ucma
Anti-upper zone of growth plate and cartilage matrix associated Antibody
半岛bd体育手机客户端 介绍
靶标:

Ucma


半岛bd体育手机客户端 别名:

1110017I16Rik; AW121955; Grp; Ucma; upper zone of growth plate and cartilage matrix associated; upper zone of growth plate and cartilage matrix associated; unique cartilage matrix-associated protein; Gla-rich protein; upper zone of growth plate and cartilage matrix associated protein; 软骨基质相关蛋白UCMA;


背景信息:
UCMA is a 138 amino acid secreted protein that is highly expressed in resting chrondrocytes in developing long bones and is thought to function in the early phase of chrondrocyte differentiation. A furin-like protease processes UCMA into an N-terminal 37 amino acid peptide and a C-terminal 74 amino acid peptide, which is referred to as Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C). Introduction of recombinant Ucma-C interferes with osteogenic differentiation of mesenchymal stem cells, MC3T3-E1 preosteoblasts and primary osteoblasts. This suggests that Ucma may be involved in the negative regulation of osteogenic differentiation of osteochondrogenic precursor cells at the cartilage-bone interface and in peripheral zones of fetal cartilage.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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