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Ppm1m抗体
半岛bd体育手机客户端 介绍
靶标:
Ppm1m 半岛bd体育手机客户端 别名: 2810423O19Rik; AW610647; C77250; PP2Ceta; Ppm1m; protein phosphatase 1M; protein phosphatase 1M; protein phosphatase 1M; PP2C-eta; PP2CE; protein phosphatase 2C eta; protein phosphatase 2C eta-2; 背景信息:
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
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