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纺锤体和着丝粒相关蛋白2抗体
半岛bd体育手机客户端 介绍
靶标：
Ska2 半岛bd体育手机客户端 别名： 1110001A07Rik； C78640； Fam33a； Ska2； spindle and kinetochore associated complex subunit 2； spindle and kinetochore associated complex subunit 2； spindle and kinetochore-associated protein 2； family with sequence similarity 33, member A； 纺锤体和着丝粒相关蛋白2； 背景信息：
Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17.SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and SKA3 which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. SKA2 may function as a prognostic gene marker for identifying lung cancer[3] as well as a proposed biomarker for suicidal tendencies and post-traumatic stress disorders.[4][5] The SKA2 gene contains one single-nucleotide polymorphism (SNP) rs7208505 located in the 3' UTR. This genetic variant containing a cytosine (existing in the less common allele) instead of thymine along with epigenetic modification (such as DNA methylation) is correlated with suicidal tendencies and post-traumatic stress
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