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肥大细胞膜抑制性受体Allergin1抗体
肥大细胞膜抑制性受体Allergin1抗体图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Anti-Milr1
Anti-mast cell immunoglobulin-like receptor 1 Antibody
半岛bd体育手机客户端 介绍
靶标:

Milr1


半岛bd体育手机客户端 别名:

Mca32; Milr1; mast cell immunoglobulin-like receptor 1; mast cell immunoglobulin-like receptor 1; allergin-1; MCA-32; allergy inhibitory receptor 1; mast cell Ag-32; mast cell antigen 32; surface protein MCA-32; 肥大细胞膜抑制性受体Allergin1;


背景信息:
As a major event in type ?? allergic reaction,degranulation of mast cells is triggered by the interaction between specific IgEs and high affinity IgE receptors (Fc??RIs) on mast cell membrane,and is followed by the release of a battery of inflammatory mediators,such as histamine,leukotrienes and arachidonic acid,and these inflammatory mediators in turn induce a series of allergic symptoms.Recently,Allergin-1 has been found to be an immunoglobulin-like receptor preferentially expressed on mast cells.The crosslinking of Allergin-1 to Fc??RIs on mast cells may inhibit the signal transduction from Fc??RIs to intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM),generate ITIM inhibitory signals,which then participate in the regulation of mast cell degranulation,and finally block the initiation of allergic inflammation.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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