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NFE4抗体
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NFE4 半岛bd体育手机客户端 别名： NF-E4； NFE4； nuclear factor, erythroid 4； nuclear factor, erythroid 4； fetal globin activator NF-E4； gamma-globin gene activator； transcription factor NF-E4； 背景信息：
The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],
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