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SCYL1抗体
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SCYL1 半岛bd体育手机客户端 别名: GKLP; HT019; NKTL; NTKL; P105; SCAR21; TAPK; TEIF; TRAP; SCYL1; SCY1 like pseudokinase 1; SCY1 like pseudokinase 1; N-terminal kinase-like protein; SCY1-like protein 1; SCY1-like, kinase-like 1; coated vesicle-associated kinase of 90 kDa; likely ortholog of mouse N-terminal kinase-like protein; telomerase regulation-associated protein; telomerase transcriptional elements-interacting factor; teratoma-associated tyrosine kinase; 背景信息:
SCY1-like 1 (S. cerevisiae), also known as SCYL1, is a human gene which is highly conserved throughout evolution. This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
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