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Pellino 2蛋白抗体
Pellino 2蛋白抗体图片
交货期: 1周
索取资料及报价
交货期:1周
半岛bd体育手机客户端 别名:Anti-PELI2
Anti-pellino E3 ubiquitin protein ligase family member 2 Antibody
半岛bd体育手机客户端 介绍
靶标:

PELI2


半岛bd体育手机客户端 别名:

PELI2; pellino E3 ubiquitin protein ligase family member 2; pellino E3 ubiquitin protein ligase family member 2; E3 ubiquitin-protein ligase pellino homolog 2; RING-type E3 ubiquitin transferase pellino homolog 2; pellino homolog 2; pellino-2; protein pellino homolog 2; Pellino 2蛋白;


背景信息:
PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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