闈舵爣锛欬p style="text-indent: 2em;">BBX

浜у搧鍒悕锛欬p style="text-indent: 2em;">ARTC1锛 HBP2锛 HSPC339锛 MDS001锛 BBX锛 BBX high mobility group box domain containing锛 BBX high mobility group box domain containing锛 HMG box transcription factor BBX锛 Ag recognized by Treg cells 1锛 BBX, HMG-box containing锛 HMG box-containing protein 2锛 bobby sox homolog锛 x 001 protein锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">BBX (HMG box transcription factor BBX, Bobby sox homolog, HMG box-containing protein 2) is a 941 amino acid protein encoded by the human gene BBX. BBX is a nuclear protein that contains one high mobility group (HMG) domain that belongs to the Sox (Sry-related HMG box) family of transcription factors. HMG proteins are thought to play a significant role in various human disorders. Disruptions and rearrangements in the genes coding for some of the HMG proteins are associated with common benign tumors. Commonly, antibodies against HMG proteins are found in patients suffering from autoimmune diseases. The SRY gene on the Y Chromosome, responsible for male sexual differentiation, contains a HMG-Box domain. Some HMG proteins have demonstrated extracellular activity as a chemokine, attracting neutrophils and mononuclear inflammatory cells to the infected sites. BBX functions as a transcription factor that is necessary for cell cycle progression from G1?to S phase.