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WDR11抗体
半岛bd体育手机客户端 介绍
靶标:
WDR11 半岛bd体育手机客户端 别名: BRWD2; DR11; HH14; SRI1; WDR15; WDR11; WD repeat domain 11; WD repeat domain 11; WD repeat-containing protein 11; WD repeat domain 15; WD repeat-containing protein 15; bromodomain and WD repeat-containing protein 2; sensitization to ricin complex subunit 1; 背景信息:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
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