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PACS1抗体
半岛bd体育手机客户端 介绍
靶标:
PACS1 半岛bd体育手机客户端 别名: MRD17; SHMS; PACS1; phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; PACS-1; cytosolic sorting protein PACS-1; 背景信息:
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008],
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