闈舵爣锛欬p style="text-indent: 2em;">DENND4C

浜у搧鍒悕锛欬p style="text-indent: 2em;">C9orf55锛 C9orf55B锛 RAB10GEF锛 bA513M16.3锛 DENND4C锛 DENN domain containing 4C锛 DENN domain containing 4C锛 DENN domain-containing protein 4C锛 DENN/MADD domain containing 4A pseudogene锛 DENN/MADD domain containing 4C锛 MAP婵€閰舵縺娲绘浜″煙铔嬬櫧4C锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">DENND4C is a 1,673 amino acid multi-pass membrane protein. DENND4C contains a dDENN domain, DENN domain, uDENN domain and a PPR (pentatricopeptide) repeat. As a result of alternative splicing, six DENND4C isoforms exist. The gene encoding DENND4C maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.