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主导控制样蛋白3抗体
半岛bd体育手机客户端 介绍
靶标:
MAML3 半岛bd体育手机客户端 别名: CAGH3; ERDA3; GDN; MAM-2; MAM2; TNRC3; mam-3; MAML3; mastermind like transcriptional coactivator 3; mastermind like transcriptional coactivator 3; mastermind-like protein 3; CAG repeat containing (glia-derived nexin I alpha); expanded repeat domain, CAG/CTG 3; polyglutamine rich; trinucleotide repeat containing 3; 主导控制样蛋白3; 背景信息:
The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.
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