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富含亮氨酸胶质瘤失活蛋白2抗体
半岛bd体育手机客户端 介绍
靶标:
LGI2 半岛bd体育手机客户端 别名: LGIL2; LGI2; leucine rich repeat LGI family member 2; leucine rich repeat LGI family member 2; leucine-rich repeat LGI family member 2; LGI1-like protein 2; leucine-rich glioma-inactivated protein 2; leucine-rich, glioma inactivated 2; 富含亮氨酸胶质瘤失活蛋白2; 背景信息:
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
宿主:Rbt |
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