闈舵爣锛欬p style="text-indent: 2em;">LAX1

浜у搧鍒悕锛欬p style="text-indent: 2em;">LAX锛 LAX1锛 lymphocyte transmembrane adaptor 1锛 lymphocyte transmembrane adaptor 1锛 lymphocyte transmembrane adapter 1锛 LAT-like membrane associated protein锛 linker for activation of x cells锛 membrane-associated adapter protein LAX锛 鑶滅浉鍏虫帴澶磋泲鐧絃AX锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">function:Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,