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硫氧还蛋白相关跨膜蛋白3抗体
半岛bd体育手机客户端 介绍
靶标:
TMX3 半岛bd体育手机客户端 别名: PDIA13; TXNDC10; TMX3; thioredoxin related transmembrane protein 3; thioredoxin related transmembrane protein 3; protein disulfide-isomerase TMX3; protein disulfide isomerase family A, member 13; thioredoxin domain containing 10; thioredoxin domain-containing protein 10; 硫氧还蛋白相关跨膜蛋白3; 背景信息:
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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