半岛bd体育手机客户端 介绍
靶标:
SLCO1C1 半岛bd体育手机客户端 别名: OATP-F; OATP1; OATP14; OATP1C1; OATPF; OATPRP5; SLC21A14; SLCO1C1; solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family member 1C1; OAT-RP-5; OATP-14; organic anion transporter F; organic anion transporter polypeptide-related protein 5; organic anion transporting polypeptide 14; solute carrier family 21 (organic anion transporter), member 14; solute carrier family 21 member 14; thyroxine transporter; 溶质载体家族蛋白21成员1C1; 背景信息:
This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009],
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