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ANGEL2蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
Angel2 半岛bd体育手机客户端 别名: 2610307I21Rik; 5730410O10Rik; AI845692; D1Ertd396e; D1Ertd654e; Angel2; angel homolog 2; angel homolog 2; protein angel homolog 2; ANGEL2蛋白; 背景信息:
ANGEL2 is a 544 amino acid protein that belongs to the CCR4 nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3???5??-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
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