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轴索过度生长抑制因子B受体抗体
半岛bd体育手机客户端 介绍
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Nus1 半岛bd体育手机客户端 别名： 1600027K07Rik； AU019165； AW538011； BC003223； D10Ertd438e； Nus1； NUS1 dehydrodolichyl diphosphate synthase subunit； NUS1 dehydrodolichyl diphosphate synthase subunit； dehydrodolichyl diphosphate synthase complex subunit Nus1； Nogo-B receptor； dehydrodolichyl diphosphate syntase complex subunit Nus1； di-trans,poly-cis-decaprenylcistransferase； ngBR； nuclear undecaprenyl pyrophosphate synthase 1 homolog； 轴索过度生长抑制因子B受体； 背景信息：
Swiss-Prot Acc.Q96E22.With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).
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