闈舵爣锛欬p style="text-indent: 2em;">RTEL1

浜у搧鍒悕锛欬p style="text-indent: 2em;">C20orf41锛 DKCA4锛 DKCB5锛 NHL锛 PFBMFT3锛 RTEL锛 RTEL1锛 regulator of telomere elongation helicase 1锛 regulator of telomere elongation helicase 1锛 regulator of telomere elongation helicase 1锛 regulator of telomere length锛 闈為湇濂囬噾娣嬪反鐦よ泲鐧斤紱

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">The RTEL1 gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms.