半岛bd体育手机客户端 介绍
靶标：
TAF9B 半岛bd体育手机客户端 别名： DN-7； DN7； TAF9L； TAFII31L； TFIID-31； TAF9B； TATA-box binding protein associated factor 9b； TATA-box binding protein associated factor 9b； transcription initiation factor TFIID subunit 9B； TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa； TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa； TBP-associated factor 9L； neuronal cell death-related protein 7； transcription initiation factor IID, 31kD subunit； transcription-associated factor TAFII31L； 转录起始因子TFIID亚基9b/神经细胞死亡相关蛋白7； 背景信息：
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.
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