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FAM152A蛋白抗体
FAM152A蛋白抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Anti-DESI2
Anti-desumoylating isopeptidase 2 Antibody
半岛bd体育手机客户端 介绍
靶标:

DESI2


半岛bd体育手机客户端 别名:

C1orf121; CGI-146; DESI; DESI1; DeSI-2; FAM152A; PNAS-4; PPPDE1; DESI2; desumoylating isopeptidase 2; desumoylating isopeptidase 2; deubiquitinase DESI2; PPPDE peptidase domain-containing protein 1; desumoylating isopeptidase 1; family with sequence similarity 152, member A; FAM152A蛋白;


背景信息:
PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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