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DNA修复甲基磺酸敏感性基因19抗体
DNA修复甲基磺酸敏感性基因19抗体图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Anti-Mms19
半岛bd体育手机客户端 介绍
靶标:

Mms19


半岛bd体育手机客户端 别名:

CG12005; Dmel\CG12005; MMS19; NEST:bs07f08; dMMS19; mms19; Mms19; Mms19; Mms19; CG12005-PB; Mms19-PB; DNA修复甲基磺酸敏感性基因19;


背景信息:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2 XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2 XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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