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Taz抗体
Taz抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Anti-Taz
Anti-Tafazzin Antibody
半岛bd体育手机客户端 介绍
靶标:

Taz


半岛bd体育手机客户端 别名:

CG8766; Dmel\CG8766; TAZ; dTAZ; tafazzin; taz; Taz; Tafazzin; Tafazzin; tafazzin; CG8766-PA; CG8766-PB; CG8766-PC; CG8766-PD; Taz-PA; Taz-PB; Taz-PC; Taz-PD; tafazzins;


背景信息:
Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3 MST2 and STK4 MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1 2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1 TAZ. WWTR1 enhances PAX8 and NKX2-1 TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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