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T淋巴细胞识别鳞状细胞癌抗原2抗体
半岛bd体育手机客户端 介绍
靶标：
DSE 半岛bd体育手机客户端 别名： DS-epi1； DSEP； DSEPI； EDSMC2； SART-2； SART2； DSE； dermatan sulfate epimerase； dermatan sulfate epimerase； dermatan-sulfate epimerase； DS epimerase； chondroitin-glucuronate 5-epimerase； squamous cell carcinoma antigen recognized by T-cells 2； T淋巴细胞识别鳞状细胞癌抗原2； 硫酸皮肤素差向异构酶(DSE)； 背景信息：
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016],
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