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早期有丝分裂抑制蛋白1抗体
半岛bd体育手机客户端 介绍
靶标:
FBXO5 半岛bd体育手机客户端 别名: EMI1; FBX5; Fbxo31; FBXO5; F-box protein 5; F-box protein 5; F-box only protein 5; F-box protein Fbx5; early mitotic inhibitor 1; 早期有丝分裂抑制蛋白1; 背景信息:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.
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