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锌指蛋白288抗体
半岛bd体育手机客户端 介绍
靶标:
ZBTB20 半岛bd体育手机客户端 别名: DPZF; HOF; ODA-8S; PRIMS; ZNF288; ZBTB20; zinc finger and BTB domain containing 20; zinc finger and BTB domain containing 20; zinc finger and BTB domain-containing protein 20; BTB/POZ zinc finger protein DPZF; dendritic cell-derived BTB/POZ zinc finger; zinc finger protein 288; 锌指蛋白288; 背景信息:
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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