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1号染色体开放阅读框77抗体
半岛bd体育手机客户端 介绍
靶标:
CHTOP 半岛bd体育手机客户端 别名: C10orf77; C1orf77; FL-SRAG; FOP; SRAG; SRAG-3; SRAG-5; pp7704; CHTOP; chromatin target of PRMT1; chromatin target of PRMT1; chromatin target of PRMT1 protein; friend of PRMT1 protein; small protein rich in arginine and glycine; 1号染色体开放阅读框77; 背景信息:
This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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