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CRB1蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
CRB1 半岛bd体育手机客户端 别名: CRB1-A; CRB1-B; CRB1-C; LCA8; RP12; CRB1; crumbs cell polarity complex component 1; crumbs cell polarity complex component 1; protein crumbs homolog 1; crumbs 1, cell polarity complex component; crumbs family member 1, photoreceptor morphogenesis associated; CRB1蛋白; 背景信息:
Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.
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