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抗体 >> 其他抗体
Cullin 9蛋白(CUL9)抗体
Cullin 9蛋白(CUL9)抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: PARC蛋白抗体
Anti-CUL9
半岛bd体育手机客户端 介绍
靶标:

CUL9


半岛bd体育手机客户端 别名:

H7AP1; PARC; CUL9; cullin 9; cullin 9; cullin-9; CUL-9; UbcH7-associated protein 1; p53-associated parkin-like cytoplasmic protein; parkin-like cytoplasmic p53 binding protein; Cullin 9蛋白(CUL9); PARC蛋白;


背景信息:
The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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