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Ⅲ型纤维连接蛋白域蛋白3A抗体
半岛bd体育手机客户端 介绍
靶标:
FNDC3A 半岛bd体育手机客户端 别名: FNDC3; HUGO; bA203I16.1; bA203I16.5; FNDC3A; fibronectin type III domain containing 3A; fibronectin type III domain containing 3A; fibronectin type-III domain-containing protein 3A; human gene expressed in odontoblasts; Ⅲ型纤维连接蛋白域蛋白3A; 背景信息:
FNDC3A is a 1,134 amino acid protein that belongs to the FNDC3 family of proteins. FNDC3A contains an N-terminal proline-rich region, nine fibronectin type-III domains (none of which contain an RGD sequence) and a hydrophobic C-terminal transmembranous helix. Expressed in a wide variety of tissues, FNDC3A localizes to Golgi vesicles and to the developing acrosome of spermatids. FNDC3A is believed to function in glycosaminoglycan and collagen synthesis. In mice, a mutation in the gene encoding FNDC3A causes male sterility due to defective adhesion between Sertoli cells and spermatids in the seminiferous epithelium. This suggests that FNDC3A plays an important role in spermatogenesis, possibly mediating or maintaining the adhesion between Sertoli cells and spermatids.
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