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周期素D结合蛋白1抗体
半岛bd体育手机客户端 介绍
靶标:
Ccndbp1 半岛bd体育手机客户端 别名: AU022347; DIP1; GCIP; Maid; SECC-8; SSEC-8; Ccndbp1; cyclin D-type binding-protein 1; cyclin D-type binding-protein 1; cyclin-D1-binding protein 1; grap2 and cyclin-D-interacting protein; maternal Id-like protein; maternal inhibition of differentiation; stage specific embryonic cDNA-8 protein; 周期素D结合蛋白1; 背景信息:
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009],
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