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驱动蛋白家族蛋白7抗体
半岛bd体育手机客户端 介绍
靶标:
Kif7 半岛bd体育手机客户端 别名: Kif7; kinesin family member 7; kinesin family member 7; kinesin-like protein KIF7; kinesin 7; 驱动蛋白家族蛋白7; 背景信息:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],
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