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I类组织相容性H-2抗原D-Dalpha链抗体
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靶标:
H2-D1 半岛bd体育手机客户端 别名: H-2D; H2-D; H2-K1; H2-D1; histocompatibility 2, D region locus 1; histocompatibility 2, D region locus 1; H-2 class I histocompatibility antigen, D-B alpha chain; H-2D cell surface glycoprotein; H2-DC1-beta transplantation antigen protein; MHC H2-D-q alpha-chain; MHC class I H-2Dp; MHC class I H2 antigen; Q5k protein; I类组织相容性H-2抗原D-Dalpha链; 背景信息:
The “classical” MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic α chains noncovalently associated with the invariant ?2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8
+T lymphocytes which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8
+T cells during T cell ontogeny.
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