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Sp140核体蛋白(SP140)抗体
半岛bd体育手机客户端 介绍
靶标:
SP140 半岛bd体育手机客户端 别名: LYSP100; LYSP100-A; LYSP100-B; SP140; SP140 nuclear body protein; SP140 nuclear body protein; nuclear body protein SP140; lymphoid-restricted homolog of Sp100; lymphoid-specific SP100 homolog; nuclear autoantigen Sp-140; speckled 140 kDa; Sp140核体蛋白(SP140); 核自身抗原SP140; 背景信息:
This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
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