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选择性剪接因子3B亚基2抗体
半岛bd体育手机客户端 介绍
靶标：
SF3B2 半岛bd体育手机客户端 别名： CFM； Cus1； SAP145； SF3B145； SF3b1； SF3b150； SF3B2； splicing factor 3b subunit 2； splicing factor 3b subunit 2； splicing factor 3B subunit 2； SAP 145； pre-mRNA splicing factor SF3b 145 kDa subunit； spliceosome associated protein 145； splicing factor 3b, subunit 2, 145kD； splicing factor 3b, subunit 2, 145kDa； 选择性剪接因子3B亚基2； 背景信息：
Splicing factor 3B subunit 2 is a protein that in humans is encoded by the SF3B2 gene. This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
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