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IVNS1ABP抗体
半岛bd体育手机客户端 介绍
靶标:
IVNS1ABP 半岛bd体育手机客户端 别名: ARA3; FLARA3; HSPC068; IMD70; KLHL39; ND1; NS-1; NS1-BP; NS1BP; IVNS1ABP; influenza virus NS1A binding protein; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; NCX downstream gene 1; NS1-binding protein; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3; kelch-like family member 39; kelch-like protein 39; 背景信息:
Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity. Protects cells from cell death induced by actin destabilization (By similarity. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20 E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro.
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