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锌指蛋白ZBTB5抗体
半岛bd体育手机客户端 介绍
靶标:
ZBTB5 半岛bd体育手机客户端 别名: ZBTB5; zinc finger and BTB domain containing 5; zinc finger and BTB domain containing 5; zinc finger and BTB domain-containing protein 5; 锌指蛋白ZBTB5; 背景信息:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr??ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Kr??ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.
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