半岛bd体育手机客户端 介绍
靶标：
IQSEC1 半岛bd体育手机客户端 别名： ARF-GEP100； ARFGEP100； BRAG2； GEP100； IDDSSBA； IQSEC1； IQ motif and Sec7 domain ArfGEF 1； IQ motif and Sec7 domain ArfGEF 1； IQ motif and SEC7 domain-containing protein 1； ADP-ribosylation factors guanine nucleotide-exchange protein 100； ADP-ribosylation factors guanine nucleotide-exchange protein 2； IQ motif and Sec7 domain 1； brefeldin A-resistant ARF-GEF2； brefeldin-resistant Arf-GEF 2 protein； epididymis secretory sperm binding protein； ADP-核糖基化因子鸟嘌呤核苷酸交换蛋白100； 背景信息：
Guanine nucleotide exchange factor for ARF1 and ARF6. Guanine nucleotide exchange factor activity is enhanced by lipid binding. Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalization of beta-1 integrin. Involved in neuronal development (Probable. In neurons, plays a role in the control of vesicle formation by endocytoc cargo. Upon long term depression, interacts with GRIA2 and mediates the activation of ARF6 to internalize synaptic AMPAR receptors (By similarity.
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