精神障碍相关GAP蛋白抗体 - 半岛电竞官方网址

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精神障碍相关GAP蛋白抗体

交货期: 1周
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交货期:	1周
半岛bd体育手机客户端别名:	Anti-SRGAP3 Anti-SLIT-ROBO Rho GTPase activating protein 3 Antibody

半岛bd体育手机客户端介绍

靶标：

SRGAP3

半岛bd体育手机客户端别名：

ARHGAP14； MEGAP； SRGAP2； WRP； SRGAP3； SLIT-ROBO Rho GTPase activating protein 3； SLIT-ROBO Rho GTPase activating protein 3； SLIT-ROBO Rho GTPase-activating protein 3； SLIT-ROBO Rho GTPase activating protein 2； WAVE-associated Rac GTPase activating protein； mental disorder-associated GAP； rho GTPase-activating protein 14；精神障碍相关GAP蛋白；

背景信息：

SRGAP3 is a 1099 amino acid protein containing 1 FCH domain, 1 Rho-GAP domain and 1 SH3 domain. Expressed highly in brain, and in lower levels in kidney, WRP is thought to play a role in cell migration through its interaction with Cdc42 and Rac1. Cdc42 and Rac1 are two intracellular signaling proteins that regulate the multistep cell migration process. WRP downregulates Cdc42 and Rac1 activity, thereby impairing actin and microtubule dynamics, the formation of protrusions, and total cell migration. Defects in the gene encoding WRP have been linked to severe idiopathic mental retardation. Three isoforms of WRP exist as a result of alternative splicing events.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。