闈舵爣锛欬p style="text-indent: 2em;">SMG7

浜у搧鍒悕锛欬p style="text-indent: 2em;">C1orf16锛 EST1C锛 SGA56M锛 SMG7锛 SMG7 nonsense mediated mRNA decay factor锛 SMG7 nonsense mediated mRNA decay factor锛 nonsense-mediated mRNA decay factor SMG7锛 EST1 telomerase component homolog C锛 EST1-like protein C锛 breast cancer-associated antigen SGA-56M锛 ever shorter telomeres 1C锛 smg-7 homolog, nonsense mediated mRNA decay factor锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">SMG7, nonsense mediated mRNA decay factor(SMG7) Homo sapiens This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011],