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DEPDC5抗体
半岛bd体育手机客户端 介绍
靶标:
DEPDC5 半岛bd体育手机客户端 别名: DEP.5; FFEVF; FFEVF1; DEPDC5; DEP domain containing 5, GATOR1 subcomplex subunit; DEP domain containing 5, GATOR1 subcomplex subunit; GATOR complex protein DEPDC5; DEP domain-containing protein 5; 背景信息:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
宿主:Rbt |
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